Abyssinone V

CAT: 0804-HY-N8265Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N8265Size:5 mg
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Description
Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V can be isolated from the stem bark of Erythrina melanacantha. Abyssinone V possesses good pharmacodynamics properties. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity[1][2].
CAS Number
[77263-11-7]
UNSPSC
12352005
Target
ATP Synthase; DNA/RNA Synthesis; HSV
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/abyssinone-v.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C(O[C@H](C(C=C2C/C=C(C)/C)=CC(C/C=C(C)/C)=C2O)C1)=CC(O)=C3)=C3O
Molecular Formula
C25H28O5
Molecular Weight
408.49
References & Citations
[1]Koch K, et al. Abyssinone V, a prenylated flavonoid isolated from the stem bark of Erythrina melanacantha increases oxidative stress and decreases stress resistance in Caenorhabditis elegans. J Pharm Pharmacol. 2019 Jun;71 (6) :1007-1016. |[2]Kwofie SK, et al. Identification of novel potential inhibitors of varicella-zoster virus thymidine kinase from ethnopharmacologic relevant plants through an in-silico approach. J Biomol Struct Dyn. 2022;40 (23) :12932-12947.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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