MYK-461

• Description :

  MYK-461 is an orally active inhibitor of cardiac myosin ATPase (IC50 = 0.3 µM in purified bovine myosin S1). It displays selectivity for cardiac myosin over skeletal myosin (IC50 = 4.7 µM) and does not induce skeletal muscle impairments. Formulations containing MYK-461 have been used for the treatment of symptomatic hypertrophic cardiomyopathy in humans and cats.

• Shipping Conditions :

  Gel Pack

• Storage Conditions :

  -20ºC

• Shelf Life :

  36 months