Terpendole C

• UNSPSC Description:

  Terpendole C, produced by Albophoma yamanashiensis, shows potent inhibitory activity against acyl-CoA: cholesterol acyltransferase (ACAT)[1].

• Target Antigen:

  Acyltransferase

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/terpendole-c.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@]12[C@]34[C@@H]([C@@]5([H])[C@](C(C)(O[C@@H](/C=C(C)/C)O5)C)([H])O[C@@]4([H])CC[C@@]1([C@]6(C7=C(C8=CC=CC=C8N7)C[C@]6([H])CC2)C)C)O3

• Molecular Weight:

  519.67

• References & Citations:

  [1]X H Huang, et al. Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. II. Structure elucidation of terpendoles A, B, C and D. J Antibiot (Tokyo). 1995 Jan;48(1):5-11.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  156967-65-6