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Terpendole I

CAT: 0804-HY-N8331Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N8331Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Terpendole I, a fungal indoloditerpene, is a ACAT (acyl-CoA: cholesterol acyltransferase) inhibitor (IC50=145 µM) [1].
CAS Number
167612-17-1
UNSPSC
12352005
Target
Acyltransferase; Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/terpendole-i.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@@]([H])(CC[C@]3([C@]45[C@]([H])(CC[C@@]32C)O[C@@H]([C@H]([C@H]4O5)O)C(O)(C)C)O)CC6=C1NC7=C6C=CC=C7
Molecular Formula
C27H35NO5
Molecular Weight
453.57
References & Citations
[1]Tomoda H, et al. Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. III. Production, isolation and structure elucidation of new components. J Antibiot (Tokyo) . 1995;48 (8) :793-804.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Microbial Metabolite

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