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Emedastine (Standard)

CAT: 0804-HY-108411RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-108411RSize:1 Each
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Description
Emedastine (Standard) is the analytical standard of Emedastine. This product is intended for research and analytical applications. Emedastine is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. Emedastine is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis[1][2][3].
CAS Number
87233-61-2
UNSPSC
12352005
Target
Histamine Receptor; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/emedastine-standard.html
Smiles
CN1CCN(C2=NC3=CC=CC=C3N2CCOCC)CCC1
Molecular Formula
C17H26N4O
Molecular Weight
302.41
References & Citations
[1]Sharif NA, et al. Emedastine: a potent, high affinity histamine H1-receptor-selective antagonist for ocular use: receptor binding and second messenger studies. J Ocul Pharmacol. 1994 Winter;10 (4) :653-64.|[2]Murota H, et al. Emedastine difumarate: a review of its potential ameliorating effect for tissue remodeling in allergic diseases. Expert Opin Pharmacother. 2009 Aug;10 (11) :1859-67.|[3]Andoh T, et al. Involvement of blockade of leukotriene B (4) action in anti-pruritic effects of emedastine in mice. Eur J Pharmacol. 2000 Oct 6;406 (1) :149-52.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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BA5404-5Emedastine
275413-01Emedastine difumarate
448160Emedastine-d3
A22158-100Emedastine 100mg
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