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Arecaidine (hydrobromide)

CAT: 0804-HY-N2368B-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2368B-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Arecaidine hydrobromide, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrobromide is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake[1][2].
CAS Number
6013-57-6
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/arecaidine-hydrobromide.html
Purity
98.0
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CCCN(C)C1)O.[H]Br
Molecular Formula
C7H12BrNO2
Molecular Weight
222.08
References & Citations
[1]D Lodge, et al. Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system. Brain Res. 1977 Nov 18;136 (3) :513-22.|[2]Valerie Voigt, et al. Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1) . J Pharm Pharmacol. 2013 Apr;65 (4) :582-90.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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