Mal-PEG3-VCP-NB

• Description:

  Mal-PEG3-VCP-NB (Compund 25c) is a degradable ADC linker containing a maleimide group, 3-unit PEG and VCP NB[1].

• UNSPSC:

  12352203

• Target:

  ADC Linker

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mal-peg3-vcp-nb.html

• Smiles:

  O=[N+]([O-])C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCCOCCOCCN3C(C=CC3=O)=O)=O)=O)=O)=O

• Molecular Formula:

  C36H45N7O14

• Molecular Weight:

  799.78

• References & Citations:

  [1]Beusker P H, et al. Novel conjugates of CC-1065 analogs and bifunctional linkers[P]. 2011-10-27.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Cleavable Linker; Protease Cleavable Linker

• CAS Number:

  1345681-77-7