Ivacaftor Carboxylic Acid

• Synonyms:

  Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-α,α-dimethyl-; 4-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-α,α-dimethylbenzeneacetic acid; Ivacaftor carboxylic acid; Ivacaftor impurity 1; 2-(5-tert-Butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid

• Hazard Statement:

  Not a hazardous substance according to GHS.

• Purity:

  >95% (HPLC)

• Smiles:

  CC(C)(C)c1cc(c(O)cc1NC(=O)C2=CNc3ccccc3C2=O)C(C)(C)C(=O)O

• Molecular Formula:

  C24 H26 N2 O5

• Molecular Weight:

  422.47

• InChI:

  InChI=1S/C24H26N2O5/c1-23(2,3)15-10-16(24(4,5)22(30)31)19(27)11-18(15)26-21(29)14-12-25-17-9-7-6-8-13(17)20(14)28/h6-12,27H,1-5H3,(H,25,28)(H,26,29)(H,30,31)

• Additionnal Information:

  IUPAC name: 2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  +4°C

• CAS Number:

  1246213-24-0