Ivacaftor

• Target :

  Autophagy|||CFTR

• Related Pathways :

  Membrane transporter/Ion channel|||Autophagy

• Purity :

  0.9998

• Bioactivity :

  Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells, respectively.

• Smiles :

  C(C)(C)(C)C1=C(NC(=O)C=2C(=O)C=3C(NC2)=CC=CC3)C=C(O)C(C(C)(C)C)=C1

• Molecular Formula :

  C24H28N2O3

• Molecular Weight :

  392.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  873054-44-5