Ivacaftor

• Description:

  Ivacaftor (VX-770, VX770) is a potent, orally bioavailable CFTR potentiator, increases G551D- and F508del CFTR-mediated Cl- secretion with EC50 of 100 nM.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  392.4907

• Molecular Formula:

  C24H28N2O3

• Notes:

  Research use only, not for human use.

• Receptor:

  F508del-CFTR|G551D-CFTR

• CAS Number:

  873054-44-5