DDR1-IN-9

DDR1-IN-9

• CAS Number: 1934246-20-4
• UNSPSC Description: DDR1-IN-9 is a selective inhibitor of DDR1 with significant kinase activity suppression, exhibiting a Kd value of 4.7 nM and an IC50 value of 9.4 nM. DDR1-IN-9 demonstrates reduced potency against a diverse panel of 400 nonmutated kinases, indicating its specificity. Additionally, DDR1-IN-9 shows favorable pharmacokinetic properties and potential therapeutic effects in a model of pulmonary fibrosis.
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/ddr1-in-9.html
• Smiles: C[C@H]1C2=CC=C(C(NC3=CC(N4C=NC(C)=C4)=CC(C(F)(F)F)=C3)=O)C=C2CN(C5=CN=CN=C5)C1
• Molecular Weight: 492.50
• References & Citations: [1]Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported