DDR1-IN-8

DDR1-IN-8

• CAS Number: 3038810-92-0
• UNSPSC Description: DDR1-IN-8 (compound 7s) is a potent inhibitor of DDR1/2, with the IC50 values of 0.045 μM and 0.126 μM, respectively. DDR1-IN-8 has anti-tumor activity[1].
• Target Antigen: Discoidin Domain Receptor
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/ddr1-in-8.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NCC1=CN(CC(N2CCN(CC2)C)=O)C3=C1C=C(F)C=C3)NC4=CC=C(C=C4F)F
• Molecular Weight: 459.46
• References & Citations: [1]Shangke Liu, et al. Design, synthesis, and biological evaluation of novel discoidin domain receptor inhibitors for the treatment of lung adenocarcinoma and pulmonary fibrosis. Eur J Med Chem. 2024 Feb 5:265:116100.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported