Undecane (Standard)

• Description:

  Undecane (Standard) is an analytical standard of Undecane (HY-N8593) .Undecane is a potent cAMP agonist with anti-allergic and anti-inflammatory activities. Undecane inhibits degranulation and the secretion of histamine and TNF-α. Undecane reverses the increased levels of p38 phosphorylation, NF-κB transcriptional activity and target cytokine/chemokine genes, including thymus and activation-regulated chemokine (TARC), macrophage-derived chemokine (MDC) and interleukin-8 (IL-8) . Undecane can be used for the study of skin inflammatory disorders, such as atopic dermatitis[1].

• UNSPSC:

  12352211

• Hazard Statement:

  H226-H304

• Target:

  Histamine Receptor; Interleukin Related; NF-κB; p38 MAPK; Reference Standards; TNF Receptor

• Type:

  Reference Standards

• Related Pathways:

  Apoptosis; GPCR/G Protein; Immunology/Inflammation; MAPK/ERK Pathway; Neuronal Signaling; NF-κB; Others

• Field of Research:

  Endocrinology; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/undecane-standard.html

• Smiles:

  CCCCCCCCCCC

• Molecular Formula:

  C11H24

• Molecular Weight:

  156.31

• Precautions:

  P210-P233-P240-P241-P242-P243-P280-P331-P370+P378-P405-P501

• References & Citations:

  [1]Choi D, Kang W, Park T. Anti-Allergic and Anti-Inflammatory Effects of Undecane on Mast Cells and Keratinocytes. Molecules. 2020;25 (7) :1554. Published 2020 Mar 28.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [1120-21-4]