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Retatrutide (TFA)

CAT: 0804-HY-P3506A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P3506A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Retatrutide (LY3437943) TFA is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) . Retatrutide TFA binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide TFA can be used for the research of obesity[1].
Product Name Alternative
LY3437943 (TFA)
UNSPSC
12352209
Target
GCGR; GLP Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/retatrutide-tfa.html
Purity
99.10
Solubility
DMSO : ≥ 100 mg/mL|H2O : 20 mg/mL (ultrasonic; adjust pH to 9 with NH3·H2O)
Smiles
[Retatrutide(TFA)]
Molecular Formula
C221H342N46O68.xC2HF3O2
Molecular Weight
4731.33 (free base)
References & Citations
[1]Tamer Coskun, et al. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept. Cell Metab. 2022 Sep 6;34 (9) :1234-1247.e9.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Phase 3

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