Lucanthone
CAT:
804-HY-B2098-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Lucanthone
- CAS Number: 479-50-5
- UNSPSC Description: Lucanthone is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1).
- Target Antigen: Autophagy; Parasite
- Type: Reference compound
- Related Pathways: Anti-infection;Autophagy
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/Lucanthone.html
- Purity: 99.75
- Solubility: DMSO : 25 mg/mL (ultrasonic)
- Smiles: O=C1C2=C(SC3=C1C=CC=C3)C(C)=CC=C2NCCN(CC)CC
- Molecular Weight: 340.48
- References & Citations: [1]Chowdhury SM, et al. Graphene nanoribbons as a drug delivery agent for lucanthone mediated therapy of glioblastoma multiforme. Nanomedicine. 2015 Jan;11(1):109-18.|[2]Carew JS, et al. Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis. J Biol Chem. 2011 Feb 25;286(8):6602-13.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Launched