BB-Cl-Amidine (hydrochloride)

BB-Cl-Amidine (hydrochloride)

• CAS Number: 2436747-41-8
• UNSPSC Description: BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor[1].
• Target Antigen: Protein Arginine Deiminase
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/bb-cl-amidine-hydrochloride.html
• Purity: 99.47
• Solubility: DMSO : 50 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C3=NC4=CC=CC=C4N3)CCCNC(CCl)=N.Cl
• Molecular Weight: 496.43
• References & Citations: [1]Knight JS, et al. Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice. Ann Rheum Dis. 2015 Dec;74(12):2199-206.Nat Cell Biol. 2021 Oct 6.|Nat Commun. 2024 Sep 3;15(1):7654.|Oncol Rep. 2023 Jul;50(1):146.|Res Sq. 2024 Jun 04.|Cell Physiol Biochem. 2024 Feb 19;58(1):63-82.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported