PFKFB3 Protein

PFKFB3 Protein_x000D_ Catalog number: B2014593_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 25 µg_x000D_ Molecular Weight or Concentration: 83 kDa_x000D_ Supplied as: Solution_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: ‚àí20¬∞C_x000D_ Keywords: PFKFB3 Protein_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: De Bock K, Georgiadou M, Schoors S, Kuchnio A, Wong BW, Cantelmo AR, Quaegebeur A, Ghesqui√®re B, Cauwenberghs S, Eelen G, Phng LK, Betz I, Tembuyser B, Brepoels K, Welti J, Geudens I, Segura I, Cruys B, Bifari F, Decimo I, Blanco R, Wyns S, Vangindertael J, Rocha S, Collins RT, Munck S, Daelemans D, Imamura H, Devlieger R, Rider M, Van Veldhoven PP, Schuit F, Bartrons R, Hofkens J, Fraisl P, Telang S, Deberardinis RJ, Schoonjans L, Vinckier S, Chesney J, Gerhardt H, Dewerchin M, Carmeliet P. Role of PFKFB3-driven glycolysis in vessel sprouting Cell. 2013 Aug 1;154(3):651-63._x000D_ 2: Zeng H, Pan T, Zhan M, Hailiwu R, Liu B, Yang H, Li P. Suppression of PFKFB3-driven glycolysis restrains endothelial-to-mesenchymal transition and fibrotic response Signal Transduct Target Ther. 2022 Sep 1;7(1):303._x000D_ 3: Cao Y, Zhang X, Wang L, Yang Q, Ma Q, Xu J, Wang J, Kovacs L, Ayon RJ, Liu Z, Zhang M, Zhou Y, Zeng X, Xu Y, Wang Y, Fulton DJ, Weintraub NL, Lucas R, Dong Z, Yuan JX, Sullivan JC, Meadows L, Barman SA, Wu C, Quan J, Hong M, Su Y, Huo Y. PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13394-13403._x000D_ 4: Min J, Zeng T, Roux M, Lazar D, Chen L, Tudzarova S. The Role of HIF1Œ±-PFKFB3 Pathway in Diabetic Retinopathy J Clin Endocrinol Metab. 2021 Aug 18;106(9):2505-2519._x000D_ 5: Nakamura MT, Yudell BE, Loor JJ. Regulation of energy metabolism by long-chain fatty acids Prog Lipid Res. 2014 Jan;53:124-44._x000D_ 6: Kovacs L, Cao Y, Han W, Meadows L, Kovacs-Kasa A, Kondrikov D, Verin AD, Barman SA, Dong Z, Huo Y, Su Y. PFKFB3 in Smooth Muscle Promotes Vascular Remodeling in Pulmonary Arterial Hypertension Am J Respir Crit Care Med. 2019 Sep 1;200(5):617-627._x000D_ 7: Thirusangu P, Ray U, Sarkar Bhattacharya S, Oien DB, Jin L, Staub J, Kannan N, Molina JR, Shridhar V. PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinoma Oncogene. 2022 Aug;41(33):4003-4017._x000D_ 8: Hu X, Xu Q, Wan H, Hu Y, Xing S, Yang H, Gao Y, He Z. PI3K-Akt-mTOR/PFKFB3 pathway mediated lung fibroblast aerobic glycolysis and collagen synthesis in lipopolysaccharide-induced pulmonary fibrosis Lab Invest. 2020 Jun;100(6):801-811._x000D_ 9: Mejias M, Gallego J, Naranjo-Suarez S, Ramirez M, Pell N, Manzano A, Su√±er C, Bartrons R, Mendez R, Fernandez M. CPEB4 Increases Expression of PFKFB3 to Induce Glycolysis and Activate Mouse and Human Hepatic Stellate Cells, Promoting Liver Fibrosis Gastroenterology. 2020 Jul;159(1):273-288._x000D_ 10: Liu J, Liu ZX, Wu QN, Lu YX, Wong CW, Miao L, Wang Y, Wang Z, Jin Y, He MM, Ren C, Wang DS, Chen DL, Pu HY, Feng L, Li B, Xie D, Zeng MS, Huang P, Lin A, Lin D, Xu RH, Ju HQ. Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming Nat Commun. 2020 Mar 20;11(1):1507. _x000D_ _x000D_ Products Related to PFKFB3 Protein can be found at Biofluids

Catalog Number: B2014593 (25 µg)

0.15

2

0.5