USP7-IN-16

USP7-IN-16

• CAS Number: 2166587-77-3
• UNSPSC Description: USP7-IN-16 (Compound 61) is a selective USP7 inhibitor with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. USP7-IN-16 exhibits antitumor activity in mice and is a promising candidate for research in the field of oncology[1].
• Target Antigen: Deubiquitinase
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/usp7-in-16.html
• Smiles: O=C1C2=C(N=CN1CC3(CCN(CC3)C([C@H]4[C@H](C5=CC=CC=C5)CN(CC4)C(C6=C(C)N=C(C7=CN=C(C)C=C7)S6)=O)=O)O)N(C8=CC(OC)=CC(OC)=C8)C=C2
• Molecular Weight: 787.93
• References & Citations: [1]Venturi L, et al. Design, Synthesis, and Activity of a Novel Series of Pyridazine-Based ALK5 Inhibitors. ACS Med Chem Lett. 2024 Oct 23;15(11):1925-1932.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported