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Estragole-d4

CAT: 0804-HY-N5060S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N5060S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Estragole-d4 is deuterated labeled Estragole. Estragole (4-Allylanisole) is a relatively nontoxic volatile terpenoid ether and major component of the essential oil from many plants. Estragole significantly triggers Apoptosis, suppresses LPS-induced intracellular ROS production. Estragole activats Nrf-2 and regulates NF-κB. Estragole has anti-toxoplasma, anti-inflammatory, anti-edema, antioxidant and immunomodulatory properties. Estragole blocks DRG neuron excitability. Estragole has improves gastric ulcer activity[1][2][3][4][5][6][7][8][9][10][11][12][13].
CAS Number
1335401-40-5
Product Name Alternative
4-Allylanisole-d4
UNSPSC
12352005
Hazard Statement
H227, H302, H315, H317, H319, H341, H351, H402, H412
Target
Isotope-Labeled Compounds; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.9
Solubility
10 mM in DMSO
Smiles
C=CCC1=C([2H])C([2H])=C(C([2H])=C1[2H])OC
Molecular Formula
C10H8D4O
Molecular Weight
152.23
Precautions
H227, H302, H315, H317, H319, H341, H351, H402, H412
References & Citations
[1]Leal-Cardoso JH, et al. Effects of estragole on the compound action potential of the rat sciatic nerve. Braz J Med Biol Res. 2004 Aug;37 (8) :1193-8.|[2]Oliveira CB, et al. Anti-Toxoplasma Activity of Estragole and Thymol in Murine Models of Congenital and Noncongenital Toxoplasmosis. J Parasitol. 2016 Jun;102 (3) :369-76.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported