Products for Research Use Only
RegisterLogin

AKT-IN-25

CAT: 0804-HY-169413Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-169413Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AKT-IN-25 (Compound 14a) is an inhibitor for Akt, that inhibits the phosphorylation of Akt, and thereby inhibits the PI3K/Akt/mTOR signaling pathway. AKT-IN-25 arrests the cell cycle at G1 phase, inhibits the cell migration of PANC-1, and inhibits the proliferation of cancer cells PANC-1, PATU-T, and SUIT-2 with IC50s of 3.05, 1.32, and 3.85 μM, respectively[1].
CAS Number
1619929-59-7
UNSPSC
12352005
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/akt-in-25.html
Smiles
O=C(N1C=C(N=N1)C2=CC=CC=C2)N3CCCCC3
Molecular Formula
C14H16N4O
Molecular Weight
256.30
References & Citations
[1]Pecoraro C, et al., Synthesis and biological evaluation of a new class of azole urea compounds as Akt inhibitors with promising anticancer activity in pancreatic cancer models. Bioorg Chem. 2024 Dec;153:107959.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-161704-01AKT-IN-23
HY-112148AKT-IN-2
HY-149841AKT-IN-17
HY-163180AKT-IN-22
HY-126257-01AKT-IN-3
HY-174254AKT-IN-28
HY-169407AKT-IN-24
HY-147513AKT-IN-12
HY-138767AKT-IN-5
HY-149842AKT-IN-18

Alternative Products

CatalogName
T203149-01AKT-IN-25
519967-01Akt
SF2784-10mMAKT inhibitor VIII (Akt inhibitor)
YP-W21449-01Mouse AKT (AKT) ELISA Kit
YP-W80334-01Porcine AKT (AKT) ELISA Kit
QY-E11913Rat phospho-AKT (p-AKT)
YP-W10057-01Human AKT (AKT) ELISA Kit
YP-W200333-01Bovine AKT (AKT) ELISA Kit
YP-W72352-01Rabbit AKT (AKT) ELISA Kit
YP-W30042-01Rat AKT (AKT) ELISA Kit

Popular Products