AKT-IN-25

CAT: 0931-T203149-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T203149-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1619929-59-7

Target

Akt

Related Pathways

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling

Bioactivity

AKT-IN-25 (Compound 14a) is an inhibitor of Akt that prevents the phosphorylation of Akt, thereby hindering the PI3K/Akt/mTOR signaling pathway. It arrests the cell cycle at the G1 phase, inhibits the migration of PANC-1 cells, and suppresses the proliferation of cancer cells PANC-1, PATU-T, and SUIT-2, with IC50 values of 3.05, 1.32, and 3.85 μM, respectively.

Smiles

O=C(N1N=NC(=C1)C=2C=CC=CC2)N3CCCCC3

Molecular Formula

C14H16N4O

Molecular Weight

256.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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AKT-IN-25

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