ST-1892

• Description:

  ST-1892 (compound 14) is a highly potent FXR agonist (EC50=7.2 nM) that can be used to study diseases or disorders caused by metabolic inflammation[1].

• UNSPSC:

  12352005

• Target:

  FXR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/st-1892.html

• Smiles:

  O=C(C1=CC=CC(C2=NC(C3=CC=CC=C3C)=NO2)=C1)O

• Molecular Formula:

  C16H12N2O3

• Molecular Weight:

  280.28

• References & Citations:

  [1]Flesch D, et al. Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties[J]. Bioorganic & medicinal chemistry, 2015, 23 (13) : 3490-3498.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1409411-32-0]