ST-1892

• UNSPSC Description:

  ST-1892 (compound 14) is a highly potent FXR agonist (EC50=7.2 nM) that can be used to study diseases or disorders caused by metabolic inflammation[1].

• Target Antigen:

  FXR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/st-1892.html

• Smiles:

  O=C(C1=CC=CC(C2=NC(C3=CC=CC=C3C)=NO2)=C1)O

• Molecular Weight:

  280.28

• References & Citations:

  [1]Flesch D, et al. Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties[J]. Bioorganic & medicinal chemistry, 2015, 23(13): 3490-3498.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1409411-32-0