Products for Research Use Only

MyD88 Polyclonal Antibody

CAT: 0749-ABP0102Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP0102Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MyD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. Myeloid differentiation primary response protein MyD88 functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Description
Rabbit Anti-MyD88 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
MYD88; Myeloid differentiation primary response protein MyD88
Gene ID
4615
Accession Number
Q99836
Reactivity
Human, Mouse, Rat, Pig
Immunogen
Synthesized peptide derived from the Internal region of human MyD88
Clonality
Polyclonal
Tag
Myeloid differentiation primary response protein MyD88
Applications
IF, WB, IHC, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
33kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
MyD88 Polyclonal Antibody detects endogenous levels of MyD88 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200; WB 1:500-1:2000; IHC 1:100-1:300; ICC 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications
Other Product Names
MYD88; Myeloid differentiation primary response protein MyD88
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q99836
Isotype
Rabbit IgG