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UBE1C Rabbit Polyclonal Antibody

CAT: 0992-R1706-14Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1706-14Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign and improperly folded proteins by targeting them for proteosome degradation. UBA3 (ubiquitin-like modifier activating enzyme 3), also known as NEDD8-activating enzyme E1 catalytic subunit or UBE1C (ubiquitin-activating enzyme E1C), is a 463 amino acid protein belonging to the ubiquitin-activating E1 family and UBA3 subfamily. Ubiquitously expressed, UBA3 acts as an activator to NEDD8, a ubiquitin-like protein, thus regulating cell division, signaling and embryogenesis. UBA3 exists as two isoforms due to alternative splicing events.
CAS Number
9007-83-4
Product Name Alternative
DKFZp566J164 antibody EC 6.3.2. antibody hUba3 antibody MGC22384 antibody NEDD8 activating enzyme E1 catalytic subunit antibody NEDD8 activating enzyme E1C antibody Nedd8 activating enzyme hUba3 antibody NEDD8-activating enzyme E1 catalytic subunit antibody NEDD8-activating enzyme E1C antibody uba3 antibody UBA3 ubiquitin activating enzyme E1 homolog antibody UBA3_HUMAN antibody UBE1C antibody Ubiquitin activating enzyme 3 antibody Ubiquitin activating enzyme E1C antibody Ubiquitin-activating enzyme 3 antibody Ubiquitin-activating enzyme E1C antibody Ubiquitin-like modifier-activating enzyme 3 antibody
Abbreviation
Ubiquitin-activating enzyme 3, UBA3, UBE1C
Swiss Prot
Q8TBC4 Human, Q8C878 Mouse, Q99MI7 Rat
Cellular Locus
Nucleus. Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human UBE1C aa 220-424 / 463.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Human liver tissue lysate, A431, HUVEC, SH-SY5Y, rat brain tissue, human pancreas tissue, mouse testis tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 52 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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