Jagged 1 Rabbit Polyclonal Antibody

Jagged 1 Rabbit Polyclonal Antibody

• Description: The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Ligands for Notch include Jagged1, Jagged2 and Delta. Jagged is a membrane protein and can activate Notch and prevent myoblast differentiation by inhibiting the expression of muscle regulatory and structural genes. It is involved in mammalian cardiovascular development and in cell-fate decisions during hematopoiesis. Jagged is expressed in adult and fetal tissues, and expression is upregulated in cervical squamous cell carcinoma. Familial Tetralogy of Fallot, the most common form of complex congenital heart disease, is caused by a mutation in the Jagged1 gene.
• Product Name Alternative: AGS antibody AHD antibody AWS antibody CD 339 antibody CD339 antibody CD339 antigen antibody Headturner antibody hJ1 antibody Htu antibody Jag 1 antibody Jag1 antibody JAG1_HUMAN antibody Jagged 1 antibody Jagged1 (Alagille syndrome) antibody Jagged1 antibody JAGL1 antibody MGC104644 antibody OTTHUMP00000030278 antibody Protein jagged-1 antibody Ser 1 antibody Ser1 antibody Serrate 1 antibody Slalom antibody
• Abbreviation: Jagged1, hJ1, JAG1, JAGL1
• CAS Number: 9007-83-4
• Swiss Prot: P78504 Human, Q9QXX0 Mouse, Q63722 Rat
• Cellular Locus: Membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Jagged 1 aa 90-144 / 1,218.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: IF-Cell, IHC-P, FC
• Positive Control: 293T, Hela, HepG2, Raw264.7, rat kidney tissue, mouse kidney tissue.
• Concentration: 1 mg/mL
• Dilution: IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 133 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No