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ESD Rabbit Polyclonal Antibody

CAT: 0992-R1511-9Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1511-9Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ESD (esterase D) is also known as S-formylglutathione hydrolase and is a 282 amino acid protein that is a member of the esterase D family. ESD is highly expressed in placenta, kidney, liver and erythrocytes, and is localized to the cytoplasm, as well as to cytoplasmic vesicles. The main function of ESD is to detoxify formaldehyde while providing energy. Formaldehyde is oxidized by ADH5 which yields S-formylglutathione. ESD then catalyzes the hydrolysis of S-formylglutathione to the reduced forms of formic acid and glutathione. In addition, ESD hydrolyzes a variety of different neutral ester substrates and can act as a carboxylesterase. ESD may also act as a cysteine hydrolase which is inactivated by thiol alkylating agents. ESD gene polymorphism can lead to reduced enzymatic activity which may cause susceptibility to many conditions, including toxic liver cirrhosis, retinoblastoma, obesity and autism.
CAS Number
9007-83-4
Product Name Alternative
EC 3.1.2.12 antibody Es-10 antibody Es10 antibody ESD antibody ESTD_HUMAN antibody Esterase 10 antibody Esterase D antibody Esterase D formylglutathione hydrolase antibody FGH antibody FGH, included antibody FLJ11763 antibody Methylumbelliferyl acetate deacetylase antibody MGC139609 antibody OTTHUMP00000018374 antibody OTTHUMP00000040929 antibody S formylglutathione hydrolase antibody S-formylglutathione hydrolase antibody S-formylglutathione hydrolase, included antibody Sid 478 antibody sid478 antibody
Abbreviation
FGH
Swiss Prot
P10768 Human, Q9R0P3 Mouse
Cellular Locus
Cytoplasm, Cytoplasmic vesicle.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within Human ESD aa 1-282 / 282.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
K562 cell lysate, mouse intestine tissue lysate, Hela, LOVO, SW480, human prostate tissue, human pancreas tissue, mouse colon tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 31 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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