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mTOR Rabbit Polyclonal Antibody

CAT: 0992-R1510-21Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1510-21Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The mechanistic target of rapamycin (mTOR), also known as the mammalian target of rapamycin and FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by the MTOR gene. mTOR is a member of the phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR links with other proteins and serves as a core component of two distinct protein complexes, mTOR complex 1 and mTOR complex 2, which regulate different cellular processes. In particular, as a core component of both complexes, mTOR functions as a serine/threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. As a core component of mTORC2, mTOR also functions as a tyrosine protein kinase that promotes the activation of insulin receptors and insulin-like growth factor 1 receptors. mTORC2 has also been implicated in the control and maintenance of the actin cytoskeleton.
CAS Number
9007-83-4
Product Name Alternative
dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1) antibody FK506 binding protein 12 rapamycin associated protein 1 antibody FK506 binding protein 12 rapamycin associated protein 2 antibody FK506 binding protein 12 rapamycin complex associated protein 1 antibody FK506-binding protein 12-rapamycin complex-associated protein 1 antibody FKBP rapamycin associated protein antibody FKBP12 rapamycin complex associated protein antibody FKBP12-rapamycin complex-associated protein 1 antibody FKBP12-rapamycin complex-associated protein antibody FLJ44809 antibody FRAP antibody FRAP1 antibody FRAP2 antibody Mammalian target of rapamycin antibody Mechanistic target of rapamycin antibody mTOR antibod MTOR_HUMAN antibody OTTHUMP00000001983 antibody RAFT1 antibody Rapamycin and FKBP12 target 1 antibody Rapamycin associated protein FRAP2 antibody Rapamycin target protein 1 antibody Rapamycin target protein antibody RAPT1 antibody Serine/threonine-protein kinase mTOR antibody
Abbreviation
mTOR
Swiss Prot
P42345 Human
Cellular Locus
Endoplasmic reticulum, mitochondrion, nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human MTOR aa 2255-2341.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, IHC-P
Positive Control
MCF-7, HepG2, rat testis tissue, rat brain tissue, mouse testis tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;WB: 1:200-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
289 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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