FPR2 Rabbit Polyclonal Antibody
CAT:
992-R1510-13
Size:
100 µL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
FPR2 Rabbit Polyclonal Antibody
- Description: The N-formyl peptide receptor (FPR) family is comprised of three members, FPR, FPR2 (also designated lipoxin A4 receptor, FPRH1 and FPRL1) and FPR3 (also designated FPRL2), all of which are chemotactic G protein-coupled receptors that contain seven transmembrane domains. These receptors are found on the surface of phagocytic leukocytes, such as neutrophils and monocytes, and each family member contains specific residues, which are responsible for determining its ligand specificity. FPR2 is a promiscuous receptor that binds to several ligands, including lipoxin A4, N-formyl-methionyl-leucyl-phenylalanine (fMLP), serum amyloid A (SAA), prion peptide and the 42 amino acid form of ∫ amyloid. Upon activation, FPR2 induces migration and calcium mobilization in human monocytes and neutrophils and is involved in inflammatory and host defense responses. FPR2 may mediate inflammation in prion and Alzheimer’s diseases, which makes it a potential target for therapeutic agents.
- Product Name Alternative: ALXR antibody FMLP-R-I antibody FMLP-R-II antibody FMLP-related receptor I antibody FMLPX antibody Formyl peptide receptor 2 antibody Formyl peptide receptor related antibody Formyl peptide receptor-like 1 antibody FPR2 antibody FPR2_HUMAN antibody FPR2A antibody FPRH1 antibody FPRH2 antibody FPRL1 antibody HM63 antibody Lipoxin A4 receptor antibody LXA4 receptor antibody LXA4R antibody N-formyl peptide receptor 2 antibody RFP antibody
- Abbreviation: FMLP-R-I,LXA4 receptor
- CAS Number: 9007-83-4
- Swiss Prot: O88536 Mouse
- Cellular Locus: Cell membrane.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthetic peptide within N-terminal mouse FPR2.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: IF-Cell, IHC-P, FC
- Positive Control: HepG2, PC-3M, human lung cancer, mouse testis tissue, human spleen tissue, Jurkat.
- Concentration: 1 mg/mL
- Dilution: IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 39 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Recombinant Antibody: No