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PTPRF/LAR Rabbit Polyclonal Antibody

CAT: 0992-R1510-12Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1510-12Size:100 µL
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Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
CAS Number
9007-83-4
Product Name Alternative
FLJ43335 antibody FLJ45062 antibody FLJ45567 antibody LAR antibody LAR protein antibody LARFN5C antibody LARS antibody LCA homolog antibody Leukocyte antigen related (LAR) PTP receptor antibody Leukocyte antigen related antibody Leukocyte antigen related PTP receptor antibody Leukocyte antigen related tyrosine phosphatase antibody Leukocyte common antigen related antibody Protein Tyrosine Phosphatase Receptor Type F antibody Protein tyrosine phosphatase receptor type F polypeptide antibody Ptprf antibody PTPRF protein antibody PTPRF_HUMAN antibody Receptor linked protein tyrosine phosphatase LAR antibody Receptor type tyrosine protein phosphatase F antibody Receptor type tyrosine protein phosphatase F precursor antibody Receptor-type tyrosine-protein phosphatase F antibody
Abbreviation
LAR
Swiss Prot
P10586 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein with Human PTPRF / LAR aa 134-650 / 1,907.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, IHC-P, FC
Positive Control
SiHa, human colon carcinoma tissue, human kidney tissue, A431.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:200-1:500;IHC-P: 1:50-1:1,000;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 213 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No