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ASH2L Rabbit Polyclonal Antibody

CAT: 0992-R1408-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1408-1Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcriptional regulator . Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters . Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3 . May play a role in hematopoiesis (PubMed:12670868). In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B .
CAS Number
9007-83-4
Product Name Alternative
ASH 2 antibody Ash2 (absent small or homeotic) like antibody Ash2 (absent, small, or homeotic) like (Drosophila) antibody ASH2 antibody ASH2 LIKE antibody ASH2 like protein antibody ASH2-like protein antibody Ash2l antibody ASH2L_HUMAN antibody ASH2L1 antibody ASH2L2 antibody Bre 2 antibody Bre2 antibody Discs 2-like antibody Drosophila absent, small, or homeotic antibody Drosophila ASH2-like antibody Set1/Ash2 histone methyltransferase complex subunit ASH2 antibody
Abbreviation
ASH2-like protein.ASH2L,Set1/Ash2 histone methyltransferase complex subunit ASH2
Swiss Prot
Q9UBL3 Human, Q91X20 Mouse
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human ASH2L aa 575-628.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Hela cell lysates, PC-12 cell lysates, mouse colon tissue, human breast carcinoma tissue, human colon tissue, Siha.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:100-1:500;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
59/57/60
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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