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ZO2 Rabbit Polyclonal Antibody

CAT: 0992-R1402-2Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1402-2Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tight junctions, or zona occludens, form a continuous barrier to fluids across the epithelium and endothelium. They function in regulation of paracellular permeability and in the maintenance of cell polarity, blocking the movement of transmembrane proteins between the apical and the basolateral cell surfaces. Zona occludens proteins ZO-1, -2, and -3 (also known as TJP1, 2, and 3) are peripheral membrane adaptor proteins that link junctional transmembrane proteins such as occludin and claudin to the actin cytoskeleton. ZO-1 and -2 are required for tight junction formation and function. In subconfluent proliferating cells, ZO-1 and ZO-2 have been shown to colocalize to the nucleus and play a role in transcriptional regulation, possibly through facilitating nuclear import/export of transcriptional regulators.
CAS Number
9007-83-4
Product Name Alternative
C9DUPq21.11 antibody DFNA51 antibody DUP9q21.11 antibody Friedreich ataxia region gene X104 (tight junction protein ZO-2) antibody MGC26306 antibody PFIC4 antibody Tight junction protein 2 antibody Tight junction protein ZO 2 antibody Tight junction protein ZO-2 antibody TJP2 antibody X104 antibody ZO 2 antibody ZO-2 antibody ZO2 antibody ZO2_HUMAN antibody Zona occludens 2 antibody Zona occludens protein 2 antibody Zonula occludens protein 2 antibody
Abbreviation
TJP2
Swiss Prot
Q9UDY2 Human, Q9Z0U1 Mouse
Cellular Locus
Cell membrane
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within C-terminal human ZO2.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
A431, F9, 293
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IF-Cell: 1:100-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 134 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No