DPY30 Rabbit Polyclonal Antibody

DPY30 Rabbit Polyclonal Antibody

• Description: As part of the MLL1/MLL complex, DPY30 is involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. DPY30 may play some role in histone H3 acetylation. In a teratocarcinoma cell, it plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. DPY30 may also play an indirect or direct role in endosomal transport. In the recent study, it showed that depletion of Dpy-30 does not affect ESC self-renewal, but significantly alters the differentiation potential of ESCs, particularly along the neural lineage.
• Product Name Alternative: Dpy-30-like protein antibody Dpy-30L antibody DPY30 antibody DPY30_HUMAN antibody HDPY-30 antibody Protein dpy-30 homolog antibody Saf19 antibody
• Abbreviation: Dpy-30L
• CAS Number: 9007-83-4
• Swiss Prot: Q9C005 Human, Q99LT0 Mouse
• Cellular Locus: Nucleus. Golgi apparatus
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Full length protein.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: IF-Cell, IHC-P
• Positive Control: NCCIT , F9, D3, human lung carcinoma tissue, mouse brain tissue.
• Concentration: 1 mg/mL
• Dilution: IHC-P: 1:100-1:200 ;IF-Cell: 1:100-1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 11kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No