Nucleolin Rabbit Polyclonal Antibody

• Description :

  Nucleolin is a protein that in humans is encoded by the NCL gene. Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Nucleolin is also able to act as a transcriptional coactivator with Chicken Ovalbumin Upstream Promoter Transcription Factor II (COUP-TFII).

• Product Name Alternative :

  C23 antibody FLJ45706 antibody MS1116 antibody NCL antibody Nucl antibody NUCL_HUMAN antibody Nucleolin antibody Protein C24 antibody

• Abbreviation :

  NCL

• Swiss Prot :

  P19338 Human

• Cellular Locus :

  Cell nucleus, cytoplasm

• Host :

  Rabbit

• Species Reactivity :

  Human

• Immunogen :

  Synthetic peptide within Human Nucleolin aa 271-320 / 710.

• Isotype :

  IgG

• Conjugation :

  Non-conjugated

• Type :

  Rabbit polyclonal Antibody

• Applications :

  WB, IF-Cell, IHC-P

• Positive Control :

  K-562 cell lysate, HeLa cell lysate, Jurkat cell lysate, HEK-293 cell lysate, A431 cell lysate, HepG2 cell lysate, A549 cell lysate, Hela, human ovary tissue.

• Concentration :

  1 mg/mL

• Dilution :

  WB: 1:1,000 ;IF-Cell: 1:50-1:100 ;IHC-P: 1:200

• Purity :

  Immunogen affinity purified.

• Form :

  Liquid

• Buffer :

  1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight :

  Predicted band size: 77 kDa

• Storage Conditions :

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody :

  No

• CAS Number :

  9007-83-4