Nucleolin Rabbit Polyclonal Antibody

Nucleolin Rabbit Polyclonal Antibody

• Description: Nucleolin is a protein that in humans is encoded by the NCL gene. Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Nucleolin is also able to act as a transcriptional coactivator with Chicken Ovalbumin Upstream Promoter Transcription Factor II (COUP-TFII).
• Product Name Alternative: C23 antibody FLJ45706 antibody MS1116 antibody NCL antibody Nucl antibody NUCL_HUMAN antibody Nucleolin antibody Protein C24 antibody
• Abbreviation: NCL
• CAS Number: 9007-83-4
• Swiss Prot: P19338 Human
• Cellular Locus: Cell nucleus, cytoplasm
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human Nucleolin aa 271-320 / 710.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: K-562 cell lysate, HeLa cell lysate, Jurkat cell lysate, HEK-293 cell lysate, A431 cell lysate, HepG2 cell lysate, A549 cell lysate, Hela, human ovary tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IF-Cell: 1:50-1:100 ;IHC-P: 1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 77 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No