iFluor™ 488 Conjugated OGT Recombinant Rabbit Monoclonal Antibody [JB44-39]

iFluor™ 488 Conjugated OGT Recombinant Rabbit Monoclonal Antibody [JB44-39]

• Description: O-linked N-acetylglucosamine (O-GlcNAc) transferase (also designated OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. O-GlcNAc transferase has been purified from rat liver. It exists as a heterotrimeric complex with two subunits of the same molecular mass and one shorter subunit. Both polypeptides are related; the short subunit band is either a proteolytic product of the polypeptide or the product of an alternative translation start site. O-GlcNAc transferase is expressed as multiple transcripts that are present in different amounts in various human tissues, with the highest levels of expression in pancreas. Immunofluorescence of human cells expressing rat O-GlcNAc transferase indicated that it is present in both the nucleus and cytosol. HeLa cells expressing O-GlcNAc transferase do not survive well during prolonged incubations, suggesting that this protein may be toxic to the cells.
• Product Name Alternative: FLJ23071 antibody GlcNAc transferase antibody HRNT1 antibody MGC22921 antibody O GlcNAc antibody O GlcNAc transferase p110 subunit antibody O GlcNAc transferase subunit p110 antibody O linked N acetylglucosamine (GlcNAc) transferase (UDP N acetylglucosamine:polypeptide N acetylglucosaminyl transferase) antibody O linked N acetylglucosamine (GlcNAc) transferase antibody O linked N acetylglucosamine transferase 110 kDa subunit antibody O-GlcNAc transferase subunit p110 antibody O-linked N-acetylglucosamine transferase 110 kDa subunit antibody ogt antibody OGT1_HUMAN antibody UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit antibody UDP N acetylglucosamine peptide N acetylglucosaminyltransferase GlcNAc transferase antibody UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit antibody UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase antibody Uridinediphospho N acetylglucosamine:polypeptide beta N acetylglucosaminyl transferase antibody
• Abbreviation: OGT
• CAS Number: 9000-83-3
• Swiss Prot: O15294 Human
• Cellular Locus: Nucleus. Cytoplasm. Membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human OGT aa 997-1,046 / 1,046.
• Isotype: IgG
• Conjugation: iFluor™ 488
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: IF-Cell
• Positive Control: Hela.
• Concentration: 1 mg/mL
• Dilution: IF-Cell: 1:75
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
• Molecular Weight: Predicted band size: 117 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes