iFluor™ 594 Conjugated E-Cadherin Recombinant Rabbit Monoclonal Antibody [SY0287]

iFluor™ 594 Conjugated E-Cadherin Recombinant Rabbit Monoclonal Antibody [SY0287]

• Description: Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin-6), R-cadherin, B-cadherin, E/P cadherin and cadherin-5. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function.
• Product Name Alternative: Arc 1 antibody CADH1_HUMAN antibody Cadherin 1 antibody cadherin 1 type 1 E-cadherin antibody Cadherin1 antibody CAM 120/80 antibody CD 324 antibody CD324 antibody CD324 antigen antibody cdh1 antibody CDHE antibody E-Cad/CTF3 antibody E Cadherin antibody E-cadherin antibody ECAD antibody Epithelial cadherin antibody epithelial calcium dependant adhesion protein antibody LCAM antibody Liver cell adhesion molecule antibody UVO antibody Uvomorulin antibody
• Abbreviation: E-cadherin, CDH1
• CAS Number: 9000-83-3
• Swiss Prot: P12830 Human
• Cellular Locus: Endosome, Cell membrane, trans-Golgi network, adherens junction.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human E-Cadherin aa 591-640 / 882.
• Isotype: IgG
• Conjugation: iFluor™ 594
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: IF-Tissue
• Positive Control: Human breast carcinoma tissue.
• Concentration: 1 mg/mL
• Dilution: IF-Tissue: 1:50
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
• Molecular Weight: Predicted band size: 97 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes