Integrin alpha 3 Mouse Monoclonal Antibody [A7H2]

Integrin alpha 3 Mouse Monoclonal Antibody [A7H2]

• Description: Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes up half of the α3β1 integrin duplex that plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin. ITGA3 encodes the integrin alpha 3 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 ('VLA-3'), very common antigen 2 ('VCA-2'), extracellular matrix receptor 1 ('ECMR1'), and galactoprotein b3 ('GAPB3').
• Product Name Alternative: AA407068 antibody Antigen identified by monoclonal antibody J143 antibody CD49 antigen like family member C antibody CD49 antigen-like family member C antibody CD49c antibody CD49c antigen antibody FLJ34631 antibody FLJ34704 antibody FRP 2 antibody FRP-2 antibody FRP2 antibody Galactoprotein B3 antibody GAP B3 antibody GAPB3 antibody Integrin alpha 3 antibody Integrin alpha-3 light chain antibody Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody ITA3_HUMAN antibody ITGA 3 antibody Itga3 antibody MSK18 antibody VCA 2 antibody VCA2 antibody Very late activation protein 3 receptor alpha 3 subunit antibody VL3A antibody VLA 3 alpha chain antibody VLA 3 subunit alpha antibody VLA-3 subunit alpha antibody VLA3a antibody
• Abbreviation: ITGA3
• CAS Number: 9007-83-4
• Swiss Prot: P26006 Human
• Cellular Locus: Cell membrane, invadopodium membrane, filopodium membrane.
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Recombinant protein within Human Integrin alpha-3 aa 51-250 / 1,051.
• Isotype: IgG2a
• Conjugation: Non-conjugated
• Type: Mouse monoclonal Antibody
• Applications: WB, IF-Cell
• Positive Control: HeLa cell lysate, HUVEC cell lysate, A431 cell lysate, human kidney tissue lysate, U-87 MG.
• Concentration: 2 mg/mL
• Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 117 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No