Integrin alpha 3 Mouse Monoclonal Antibody [A7H2]

• Description:

  Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes up half of the α3β1 integrin duplex that plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin. ITGA3 encodes the integrin alpha 3 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 ('VLA-3'), very common antigen 2 ('VCA-2'), extracellular matrix receptor 1 ('ECMR1'), and galactoprotein b3 ('GAPB3').

• Product Name Alternative:

  AA407068 antibody Antigen identified by monoclonal antibody J143 antibody CD49 antigen like family member C antibody CD49 antigen-like family member C antibody CD49c antibody CD49c antigen antibody FLJ34631 antibody FLJ34704 antibody FRP 2 antibody FRP-2 antibody FRP2 antibody Galactoprotein B3 antibody GAP B3 antibody GAPB3 antibody Integrin alpha 3 antibody Integrin alpha-3 light chain antibody Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody ITA3_HUMAN antibody ITGA 3 antibody Itga3 antibody MSK18 antibody VCA 2 antibody VCA2 antibody Very late activation protein 3 receptor alpha 3 subunit antibody VL3A antibody VLA 3 alpha chain antibody VLA 3 subunit alpha antibody VLA-3 subunit alpha antibody VLA3a antibody

• Abbreviation:

  ITGA3

• Swiss Prot:

  P26006 Human

• Cellular Locus:

  Cell membrane, invadopodium membrane, filopodium membrane.

• Host:

  Mouse

• Species Reactivity:

  Human

• Immunogen:

  Recombinant protein within Human Integrin alpha-3 aa 51-250 / 1,051.

• Isotype:

  IgG2a

• Conjugation:

  Non-conjugated

• Type:

  Mouse monoclonal Antibody

• Applications:

  WB, IF-Cell

• Positive Control:

  HeLa cell lysate, HUVEC cell lysate, A431 cell lysate, human kidney tissue lysate, U-87 MG.

• Concentration:

  2 mg/mL

• Dilution:

  WB: 1:500-1:2,000 ;IF-Cell: 1:100

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 117 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4