CDX4 Rabbit Polyclonal Antibody

• Description:

  The transcription factor encoded by the CDX4 gene participates in the formation of extra-embryonic tissues, anterior-posterior patterning and blood formation during embryogenesis. It does so through the regulation of Hox gene expression. Before placentation takes place, CDX4 plays a role in its development. CDX4 mutants are born healthy and are fertile, however its importance is revealed in compound CDX mutants. Compound mutants carrying one CDX2 null allele and homozygous null for CDX4 fail to generate posterior tissue caudal to the hindlimbs and most of these embryos die around embryonic day 10.5 from lack of placental development. Around 10% of this phenotype may progress to full term, but then die shortly after birth. Upon inspection the morphogenesis of ano-rectal and urethral tissues was observed.

• Product Name Alternative:

  Caudal-type homeobox protein 4 antibody CDX4 antibody CDX4_HUMAN antibody Homeobox protein CDX-4 antibody

• Abbreviation:

  Homeobox protein CDX-4 Caudal-type homeobox protein 4

• Swiss Prot:

  O14627 Human, Q07424 Mouse

• Cellular Locus:

  Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide within human CDX4 aa 50-100 / 284.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IHC-P

• Positive Control:

  Hela cell lysate, 293 cell lysate, rat cerebellum tissue, mouse testis tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:2,000;IHC-P: 1:100-1:500

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  31 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4