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SOX17 Rabbit Polyclonal Antibody

CAT: 0992-HA500476Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500476Size:100 µL
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Description
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal development of the definitive gut endoderm. Required for normal looping of the embryonic heart tube. Plays an important role in embryonic and postnatal vascular development, including development of arteries. Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX18. Required for the generation and maintenance of fetal hematopoietic stem cells, and for fetal hematopoiesis. Probable transcriptional activator in the premeiotic germ cells.
CAS Number
9007-83-4
Product Name Alternative
FLJ22252 antibody SOX17 antibody SOX17_HUMAN antibody SRY (sex determining region Y) box 17 antibody SRY box 17 antibody SRY related HMG box transcription factor SOX17 antibody Transcription factor SOX-17 antibody Transcription factor SOX17 antibody VUR3 antibody
Abbreviation
SOX17
Swiss Prot
Q9H6I2 Human, Q61473 Mouse,
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human SOX17 aa 1-50 / 414.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, FC
Positive Control
SKOV-3 cell lysate, HepG2 cell lysate, Hela cell lysate, mouse testis tissue lysate, rat testis tissue lysate, rat brain tissue lysate, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;FC: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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