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PFKP Rabbit Polyclonal Antibody

CAT: 0992-HA500472Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500472Size:100 µL
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Description
Phosphofructokinase, platelet, also known as PFKP is an enzyme which in humans is encoded by the PFKP gene. The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose 6-phosphate to fructose 1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM) and liver (PFKL) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Full tetrameric phosphofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Product Name Alternative
1200015H23Rik antibody 6 phosphofructokinase type C antibody 6 phosphofructokinase, platelet type antibody 6-phosphofructokinase antibody 6-phosphofructokinase type C antibody 9330125N24Rik antibody FLJ40226 antibody K6PP antibody K6PP_HUMAN antibody MGC105718 antibody PFK C antibody PFK, fibroblast type antibody PFK-C antibody PFKF antibody PFKP antibody Phosphofructo 1 kinase isozyme C antibody Phosphofructo-1-kinase isozyme C antibody Phosphofructokinase 1 antibody Phosphofructokinase platelet antibody Phosphohexokinase antibody platelet type antibody
Abbreviation
PFKP
Swiss Prot
Q01813 Human, Q9WUA3 Mouse, P47860 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human PFKP aa 601-784 / 784.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
A549 cell lysate, mouse lung tissue lysate, rat lung tissue lysate, human prostate carcinoma tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
86 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No