PFKP Rabbit Polyclonal Antibody
CAT:
992-HA500472
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PFKP Rabbit Polyclonal Antibody
- Description: Phosphofructokinase, platelet, also known as PFKP is an enzyme which in humans is encoded by the PFKP gene. The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose 6-phosphate to fructose 1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM) and liver (PFKL) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Full tetrameric phosphofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.
- Product Name Alternative: 1200015H23Rik antibody 6 phosphofructokinase type C antibody 6 phosphofructokinase, platelet type antibody 6-phosphofructokinase antibody 6-phosphofructokinase type C antibody 9330125N24Rik antibody FLJ40226 antibody K6PP antibody K6PP_HUMAN antibody MGC105718 antibody PFK C antibody PFK, fibroblast type antibody PFK-C antibody PFKF antibody PFKP antibody Phosphofructo 1 kinase isozyme C antibody Phosphofructo-1-kinase isozyme C antibody Phosphofructokinase 1 antibody Phosphofructokinase platelet antibody Phosphohexokinase antibody platelet type antibody
- Abbreviation: PFKP
- CAS Number: 9007-83-4
- Swiss Prot: Q01813 Human, Q9WUA3 Mouse, P47860 Rat
- Cellular Locus: Cytoplasm.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Recombinant protein within human PFKP aa 601-784 / 784.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB, IHC-P
- Positive Control: A549 cell lysate, mouse lung tissue lysate, rat lung tissue lysate, human prostate carcinoma tissue, mouse brain tissue.
- Concentration: 1 mg/mL
- Dilution: WB: 1:1,000-1:5,000 ;IHC-P: 1:50-1:200
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: 86 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: No