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CPN1 Rabbit Polyclonal Antibody

CAT: 0992-HA500462Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500462Size:100 µL
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Description
Carboxypeptidase N catalytic chain is an enzyme that in humans is encoded by the CPN1 gene.Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer composed of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.In melanocytic cells CPN1 gene expression may be regulated by MITF.
CAS Number
9007-83-4
Product Name Alternative
ACBP antibody Anaphylatoxin inactivator antibody Arginine carboxypeptidase antibody Carboxypeptidase N catalytic chain antibody Carboxypeptidase N polypeptide 1 50 kD antibody Carboxypeptidase N polypeptide 1 antibody Carboxypeptidase N small subunit antibody Carboxypeptidase N subunit 1 antibody CBPN_HUMAN antibody CPN antibody CPN1 antibody Kininase 1 antibody Kininase-1 antibody Kininase1 antibody Lysine carboxypeptidase antibody Plasma carboxypeptidase B antibody SCPN antibody Serum carboxypeptidase N antibody
Abbreviation
Carboxypeptidase N catalytic chain CPN Anaphylatoxin inactivator Arginine carboxypeptidase Carboxypeptidase N polypeptide 1 Carboxypeptidase N small subunit Kininase-1 Lysine carboxypeptidase Plasma carboxypeptidase B Serum carboxypeptidase N SCPN
Swiss Prot
P15169 Human, Q9JJN5 Mouse
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within human CPN1 aa 1-200 / 458.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
Hela cell lysate, Raji cell lysate, mouse pancreas tissue lysate, LOVO.
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
52 kDa (Predicted band size)
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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