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Inversin Rabbit Polyclonal Antibody

CAT: 0992-HA500442Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500442Size:100 µL
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Description
Inversin is a protein that in humans is encoded by the INVS gene. This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Two transcript variants encoding distinct isoforms have been identified for this gene. INVS has been shown to interact with NPHP1.
CAS Number
9007-83-4
Product Name Alternative
INV antibody Inversion of embryo turning homolog antibody inversion of embryonic turning antibody INVS antibody Nephrocystin 2 antibody Nephrocystin-2 antibody Nephrocystin2 antibody nephronophthisis 2 (infantile) antibody NPH2 antibody NPHP2 antibody
Abbreviation
INVS
Swiss Prot
Q9Y283 Human, O89019 Mouse,
Cellular Locus
Cytoplasm, Membrane, Nucleus.
Host
Rabbit
Species Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein within human Inversin aa 901-1,050 / 1,065.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
HepG2 cell lysate, K562 cell lysate, 293T cell lysate, 293 cell lysate, rat brain tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 118 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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