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UBE2I Rabbit Polyclonal Antibody

CAT: 0992-HA500401Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500401Size:100 µL
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Description
Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity. This protein is involved in the pathway protein sumoylation, which is part of Protein modification. Expressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus.
CAS Number
9007-83-4
Product Name Alternative
C358B7.1 antibody p18 antibody SUMO 1 protein ligase antibody SUMO conjugating enzyme UBC9 antibody SUMO-conjugating enzyme UBC9 antibody SUMO-protein ligase antibody SUMO1 protein ligase antibody UBC9 antibody UBC9_HUMAN antibody UBCE9 antibody Ube2i antibody Ubiquitin carrier protein 9 antibody Ubiquitin carrier protein antibody Ubiquitin carrier protein I antibody Ubiquitin conjugating enzyme 9 antibody Ubiquitin conjugating enzyme E2I (homologous to yeast UBC9) antibody Ubiquitin conjugating enzyme E2I (UBC9 homolog, yeast) antibody Ubiquitin conjugating enzyme UbcE2A antibody Ubiquitin like protein SUMO 1 conjugating enzyme antibody Ubiquitin protein ligase E2I antibody Ubiquitin-conjugating enzyme E2 I antibody Ubiquitin-protein ligase I antibody
Abbreviation
SUMO-conjugating enzyme UBC9 RING-type E3 SUMO transferase UBC9 SUMO-protein ligase Ubiquitin carrier protein 9 Ubiquitin carrier protein I Ubiquitin-conjugating enzyme E2 I Ubiquitin-protein ligase I p18 UBE2I UBC9 UBCE9
Swiss Prot
P63279 Human, P63281 Rat
Cellular Locus
Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within human UBE2I aa 2-158.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
HepG2 cell lysate, 293T cell lysate, Hela cell lysate, Jurkat cell lysate, PC-12 cell lysates, rat large intestine tissue.
Concentration
1.92 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:800
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 18 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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