PLCB2 Rabbit Polyclonal Antibody

CAT: 0992-HA500399Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-HA500399Size:100 µL
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Description
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene. The gene codes for the enzyme phospholipase C β2. The enzyme catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11, as well as G-beta gamma subunits. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
CAS Number
9007-83-4
Product Name Alternative
1-phosphatidylinositol-4 antibody 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 antibody 5-bisphosphate phosphodiesterase beta-2 antibody FLJ38135 antibody Phosphoinositide phospholipase C-beta-2 antibody Phospholipase C-beta-2 antibody PLC-beta-2 antibody Plcb2 antibody PLCB2_HUMAN antibody
Abbreviation
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 Phosphoinositide phospholipase C-beta-2 Phospholipase C-beta-2 PLC-beta-2 PLCB2
Swiss Prot
Q00722 Human
Cellular Locus
Cytosol.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human PLCB2 aa 950-1185.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
HL-60 cell lysate, THP-1 cell lysate, SiHa.
Concentration
1.99 mg/mL
Dilution
WB: 1:2,000;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 134 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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