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IFNGR2 Rabbit Polyclonal Antibody

CAT: 0992-HA500363Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500363Size:100 µL
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Description
Interferon gamma receptor 2 also known as IFN-γR2 is a protein which in humans is encoded by the IFNGR2 gene. This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a multimer of two IFN-γR1 chains (encoded by IFNGR1) and two IFN-γR2 chains. Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding. Defects in IFNGR2 are a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. All known mutations in IFNGR2 are collected in the IFNGR2 mutation database.
CAS Number
9007-83-4
Product Name Alternative
Interferon gamma receptor 2Imported antibody IFN-gamma receptor 2 antibody IFN-gamma-R2 antibody Interferon gamma receptor accessory factor 1 antibody AF-1 antibody Interferon gamma receptor beta-chain antibody IFN-gamma-R-beta antibody Interferon gamma transducer 1 antibody IFNGR2 antibody IFNGT1 antibody
Abbreviation
Interferon gamma receptor 2Imported IFN-gamma receptor 2 IFN-gamma-R2 Interferon gamma receptor accessory factor 1 AF-1 Interferon gamma receptor beta-chain IFN-gamma-R-beta Interferon gamma transducer 1 IFNGR2 IFNGT1
Swiss Prot
P38484 Human,
Cellular Locus
Endoplasmic reticulum, Plasma membrane, Golgi apparatus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human INGR2 22-71.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
Jurkat cell lysate, Hela cell lysate, A431 cell lysate, human skeletal muscle tissue lysates, SH-SY5Y.
Concentration
1.8 mg/mL
Dilution
WB: 1:500 ;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 38 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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