IFNGR2 Rabbit Polyclonal Antibody

IFNGR2 Rabbit Polyclonal Antibody

• Description: Interferon gamma receptor 2 also known as IFN-γR2 is a protein which in humans is encoded by the IFNGR2 gene. This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a multimer of two IFN-γR1 chains (encoded by IFNGR1) and two IFN-γR2 chains. Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding. Defects in IFNGR2 are a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. All known mutations in IFNGR2 are collected in the IFNGR2 mutation database.
• Product Name Alternative: Interferon gamma receptor 2Imported antibody IFN-gamma receptor 2 antibody IFN-gamma-R2 antibody Interferon gamma receptor accessory factor 1 antibody AF-1 antibody Interferon gamma receptor beta-chain antibody IFN-gamma-R-beta antibody Interferon gamma transducer 1 antibody IFNGR2 antibody IFNGT1 antibody
• Abbreviation: Interferon gamma receptor 2Imported IFN-gamma receptor 2 IFN-gamma-R2 Interferon gamma receptor accessory factor 1 AF-1 Interferon gamma receptor beta-chain IFN-gamma-R-beta Interferon gamma transducer 1 IFNGR2 IFNGT1
• CAS Number: 9007-83-4
• Swiss Prot: P38484 Human,
• Cellular Locus: Endoplasmic reticulum, Plasma membrane, Golgi apparatus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human INGR2 22-71.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell
• Positive Control: Jurkat cell lysate, Hela cell lysate, A431 cell lysate, human skeletal muscle tissue lysates, SH-SY5Y.
• Concentration: 1.8 mg/mL
• Dilution: WB: 1:500 ;IF-Cell: 1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 38 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No