Proteasome 20S beta 6 Rabbit Polyclonal Antibody

• Description:

  In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S Proteasome. The 26S Proteasome is a protease complex that selectively breaks down proteins that have been modified by polyubiquitin chains. It is made up of two multisubunit complexes: the 20S Proteasome chamber, which serves as the proteolytic core of the complex and two 19S regulatory particles which recognize and unfold ubiquitinated proteins. The 20S Proteasome chamber contains α subunits (which are structural) and β subunits (which are predominantly catalytic). The outer two rings in the proteasome consist of seven α subunits each, and the inner two rings each consist of seven β subunits. PSMB6 (proteasome (prosome, macropain) subunit, β type, 6), also known as LMPY (PSY large multifunctional protease Y), macropain δ chain, proteasome δ chain or proteasome subunit Y, is a β subunit of the 20S Proteasome and, upon stimulation with IFN-γ, can be displaced by LMP2.

• Product Name Alternative:

  DELTA antibody LMPY antibody Macropain delta chain antibody MGC5169 antibody Multicatalytic endopeptidase complex delta chain antibody Proteasome (prosome macropain) subunit beta type 6 antibody Proteasome beta 6 subunit antibody Proteasome catalytic subunit 1 antibody Proteasome delta chain antibody Proteasome subunit beta 6 antibody Proteasome subunit beta type 6 antibody Proteasome subunit beta type-6 antibody Proteasome subunit delta antibody Proteasome subunit Y antibody PSB6_HUMAN antibody PSMB6 antibody PSY large multifunctional protease Y antibody Y antibody

• Abbreviation:

  PSMB6

• Swiss Prot:

  P28072 Human, Q60692 Mouse, P28073 Rat

• Cellular Locus:

  Cytoplasm, Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within Human Proteasome 20S beta 6 aa 21-239 / 239.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, FC

• Positive Control:

  Hela cell lysate, Jurkat cell lysate, mouse colon tissue lysate, mouse kidney tissue lysate, rat kidney tissue lysate, NIH/3T3, mouse brain tissue, Hela.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500;IF-Cell: 1:200;IHC-P: 1:1,000;FC: 1:500-1:1,000

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 25 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4