TRPV6 Rabbit Polyclonal Antibody

TRPV6 Rabbit Polyclonal Antibody

• Description: Calcium selective cation channel that mediates Ca2+ uptake in various tissues, including the intestine . Important for normal Ca2+ ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification . Inactivation includes both a rapid Ca2+-dependent and a slower Ca2+-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg2+ in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
• Product Name Alternative: ABP/ZF antibody ABPZF antibody Alu binding protein with zinc finger domain antibody Calcium channel CaT1 antibody Calcium transport protein 1 antibody CaT L antibody CaT Like antibody CaT-L antibody CaT-like antibody CaT1 antibody ecac antibody ECaC2 antibody Epithelial apical membrane calcium transporter/channel CaT1 antibody Epithelial calcium channel 2 antibody Epithelial calcium channel antibody HSA277909 antibody LP6728 antibody MGC162545 antibody NUDC antibody Transient receptor potential cation channel subfamily V member 6 antibody TrpV6 antibody TRPV6_HUMAN antibody ZFAB antibody
• Abbreviation: Transient receptor potential cation channel subfamily V member 6:Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2,TRPV6 TrpV6,CaT-like,CaT-L
• CAS Number: 9007-83-4
• Swiss Prot: Q9H1D0 Human, Q91WD2 Mouse, Q9R186 Rat
• Cellular Locus: Cell membrane, Membrane
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide corresponding to C terminal of Human TRPV6 .
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P, IF-Cell, FC
• Positive Control: SW480 cell lysate, SK-Br-3 cell lysate, HepG2, HT-29, rat testis tissue, human kidney tissue, mouse colon tissue, human placenta tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:200 ;FC: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 87 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No