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TNFR2 Rabbit Polyclonal Antibody

CAT: 0992-HA500332Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500332Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
CAS Number
9007-83-4
Product Name Alternative
CD120b antibody p75 antibody p75 TNF receptor antibody p75TNFR antibody p80 TNF alpha receptor antibody p80 TNF-alpha receptor antibody Soluble TNFR1B variant 1 antibody TBP-2 antibody TBPII antibody TNF R II antibody TNF R2 antibody TNF R75 antibody TNF-R2 antibody TNF-RII antibody TNFBR antibody TNFR-II antibody TNFR1B antibody TNFR2 antibody TNFR80 antibody TNFRII antibody Tnfrsf1b antibody TNR1B_HUMAN antibody Tumor necrosis factor beta receptor antibody Tumor necrosis factor binding protein 2 antibody Tumor necrosis factor receptor 2 antibody Tumor necrosis factor receptor superfamily member 1B antibody Tumor necrosis factor receptor type II antibody Tumor necrosis factor-binding protein 2 antibody
Abbreviation
TNFRSF1B
Swiss Prot
P20333 Human, P25119 Mouse, Q80WY6 Rat
Cellular Locus
Cell membrane, Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human TNFR2 aa 20-461 / 461.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IHC-P, FC
Positive Control
Rat epididymis tissue, human uterus tissue, mouse testis tissue, HepG2.
Concentration
1 mg/mL
Dilution
IHC-P:1:50-1:100 ;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 1%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
48 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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