Products for Research Use Only
RegisterLogin

PLK1 Rabbit Polyclonal Antibody

CAT: 0992-HA500281Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2
1 / 2
CAT#:0992-HA500281Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. PLK1 is high on non-attached kinetochores suggesting a role of PLK1 in kinetochore attachment or in spindle assembly checkpoint (SAC) regulation. Required for kinetochore localization of BUB1B. Regulates the dissociation of cohesin from chromosomes by phosphorylating cohesin subunits such as STAG2/SA2.
CAS Number
9007-83-4
Product Name Alternative
Cell cycle regulated protein kinase antibody PLK 1 antibody PLK antibody PLK-1 antibody plk1 antibody PLK1_HUMAN antibody Polo like kinase 1 antibody Polo-like kinase 1 antibody Serine/threonine protein kinase 13 antibody Serine/threonine protein kinase PLK1 antibody Serine/threonine-protein kinase 13 antibody Serine/threonine-protein kinase PLK1 antibody STPK 13 antibody STPK13 antibody
Abbreviation
Serine/threonine-protein kinase PLK1 Polo-like kinase 1 PLK-1 Serine/threonine-protein kinase 13 STPK13
Swiss Prot
P53350 Human, Q07832 Mouse
Cellular Locus
Centromere, Chromosome, Cytoplasm, Cytoskeleton, Kinetochore, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within human PLK1 aa 1-50 / 603.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, FC
Positive Control
HeLa whole cell lysate, HeLa treated with 100nM Nocodazole for 24 hours whole cell lysate, HeLa treated with 2mM thymidine for 16 hours then treated with 100nM Nocodazole for 24 hours whole cell lysate, HT-29 whole cell lysate, HT-29 treated with 100nM Nocodazole for 24 hours whole cell lysate, HT-29 treated with 2mM thymidine for 16 hours then treated with 100nM Nocodazole for 24 hours whole cell lysate, HepG2 cell lysate, Hela cell lysate, mouse testis tissue lysate, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;FC: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 68 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Related Products

CatalogName
HA750944PLK1 Recombinant Rabbit monoclonal Antibody
HA722118PLK1 Recombinant Rabbit Monoclonal Antibody [PSH04-35]
ET1701-33Phospho-PLK1 (T210) Recombinant Rabbit Monoclonal Antibody [JJ20-58]
ER1901-73GABARAPL2 Rabbit Polyclonal Antibody
ER2001-53Transferrin Rabbit Polyclonal Antibody
ER1802-12LSD1 Rabbit Polyclonal Antibody
HA500270AIM2 Rabbit Polyclonal Antibody
HA500595TMEM184A Rabbit polyclonal Antibody
HA500594HERC6 Rabbit polyclonal Antibody
HA500591COL4A3 Rabbit polyclonal Antibody

Alternative Products

CatalogName
APRab16275-01Plk1 Rabbit Polyclonal Antibody
NBP2-49014-25ulRabbit Polyclonal PLK1 Antibody

Popular Products