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SFT Rabbit Polyclonal Antibody

CAT: 0992-HA500229Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500229Size:100 µL
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Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Product Name Alternative
E2 (17)KB1 antibody SFT antibody Stimulator of Fe transport antibody UB2D1_HUMAN antibody UBC 4/5 antibody UBC4/5 antibody UBC4/5 homolog antibody UBC4/5, S. cerevisiae, homolog of antibody UBCH 5 antibody UBCH 5A antibody UbcH5 antibody UBCH5A antibody Ube2d1 antibody Ubiquitin carrier protein antibody Ubiquitin carrier protein D1 antibody Ubiquitin conjugating enzyme E2 17 kDa 1 antibody Ubiquitin conjugating enzyme E2 D1 antibody Ubiquitin conjugating enzyme E2D 1 (UBC4/5 homolog yeast) antibody Ubiquitin conjugating enzyme E2D 1 antibody Ubiquitin conjugating enzyme UBCH5A antibody Ubiquitin protein ligase D1 antibody Ubiquitin-conjugating enzyme E2 D1 antibody Ubiquitin-conjugating enzyme E2 (17)KB 1 antibody Ubiquitin-conjugating enzyme E2-17 kDa 1 antibody Ubiquitin-protein ligase D1 antibody
Abbreviation
UBE2D1
Swiss Prot
P51668 Human, P61080 Mouse, D3ZDK2 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human SFT aa 1-147.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Hela cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, rat skeletal muscle tissue lysate, mouse liver tissue lysate, rat kidney tissue, human breast tissue, mouse skeletal muscle tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:400
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
17 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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