PFKFB2 Rabbit Polyclonal Antibody

CAT: 0992-HA500200Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-HA500200Size:100 µL
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Description
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
CAS Number
9007-83-4
Product Name Alternative
6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 2 antibody 6-bisphosphatase antibody 6-P2ase 2 antibody 6-P2ASE heart-type isozyme antibody 6PF 2 K/Fru 2 6 P2ASE heart type isozyme antibody 6PF-2-K/Fru-2 antibody 6PF-2-K/Fru-26-P2ase 2 antibody 6PF-2-K/Fru-26-P2ase heart-type isozyme antibody F262_HUMAN antibody Fructose 2 6 bisphosphatase cardiac isozyme antibody Fructose-2 antibody PFK 2/FBPase 2 antibody PFK/FBPase 2 antibody PFKFB cardiac antibody PFKFB2 antibody
Abbreviation
PFKFB2
Swiss Prot
O60825 Human, P70265 Mouse
Cellular Locus
Cytosol, Nucleoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within human PFKFB2 aa 455-505.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Hela cell lysate, 293T cell lysate, mouse kidney tissue lysate, human thyroid tissue, human uterus tissue, mouse heart tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
58 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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